Mechanical Tissue Resuscitation: Novel Negative-Pressure Wound Therapy

Researchers at Wake Forest seeking a successful negative-pressure wound therapy for internal injuries such as traumatic brain injury, stroke and cardiovascular reperfusion injury and tissue and bone injuries have found that the size and extent of damaged tissue can be significantly reduced by using a new device to prevent cell death. Mechanical Tissue Resuscitation, tested in rat and pig models, uses negative pressure to create an environment that fosters cell survival and tissue growth.

Louis C. Argenta, MD, and Michael Morykwas, PhD, professors in Wake Forest’s Department of Plastic Surgery and Reconstructive Surgery, and a multidisciplinary team of colleagues at Wake Forest have a 15+ year history of inventing, developing and working with negative-pressure wound therapy devices to successfully treat wounds and burns. Over 100 products arising from their discoveries have generated more than $1 billion in revenue for licensing partners.

Mechanical Tissue Resuscitation, their newest technology, is now available for license and offers industry partners with the potential for a substantial return on investment.

Begin the conversation. Contact us at to learn more about opportunities to license Mechanical Tissue Resuscitation.

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