Soluble Hyperthermic Particles Destroy Cancer Cells, Fibroids and Cellulite
This novel soluble hyperthermic particles technology offers a soluble compound capable of heating and ablating unwanted tissues for a wide range of applications while producing minimal biocompatibility issues.
Researchers at Wake Forest University and Wake Forest School of Medicine have developed novel soluble hyperthermic particles that are capable of generating hyperthermia to destroy cancer cells. Upon stimulation with a laser, the particles produce heat, which has been shown to reduce total colorectal cancer cell viability to 5-10%. This technology has potential for use in the treatment of cancer or other diseases involving hyperplastic tissue.
Hyperthermia-induced ablation is emerging as a less invasive and more efficient alternative to surgical means of removing solid tumors or hyperplastic tissues. Most hyperthermic technologies available rely on metal-based compounds, which are less thermally stable and do not catabolize in the body.
- The soluble hyperthermic particles have been validated in vitro using HCT116 and RKO colorectal cancer cells.
- In vivo animal testing is currently ongoing.
- Nicole Levi, PhD, Department of Plastic Surgery
- Christopher MacNeill, PhD, Department of Plastic Surgery
- David L. Carroll, PhD, Department of Physics
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John Druga, MS, MBA
Licensing Director, Technology Commercialization