Stories of Medical Innovation

Wake Forest Scientists Co-Invent Imaging System to Improve Cancer Surgery

Scientists at Wake Forest Baptist Medical Center have helped develop a new imaging system to improve the detection of malignant tissue during cancer surgery.

The system uses a fluorescent dye that distinguishes malignant from healthy tissue when illuminated by a hand-held laser, allowing surgeons to determine in real-time if a surgery has effectively removed all tumor tissue.

The system may also help decrease the recurrence of cancer after surgery, says Aaron Mohs, PhD, assistant professor of regenerative medicine at Wake Forest Baptist. “Being able to quickly scan a tumor during surgery to visualize tumor tissue from non-tumor tissue is an unmet clinical need,” says Mohs, who invented the system along with Michael C. Mancini at Spectropath Inc. and Shuming Nie from Emory University and Georgia Institute of Technology.

Mohs and his Wake Forest research team have received a $1.37 million research grant from the National Institute of Biomedical Imaging and Bioengineering to conduct testing of the system in rodents.

Learn more about this new imaging system from Wake Forest Baptist.