Stories of Medical Innovation

New Flagellin-based Vaccine May Put the Bubonic Plague to Rest

Rarely does one scientist have the opportunity to witness the complete lifecycle of a therapeutic innovation, from concept to consumable product. Steve Mizel, PhD, is on the cusp of experiencing just this.

Mizel, a Professor of Microbiology and Immunology at Wake Forest School of Medicine, has created a biodefense vaccine against bubonic plague that has just completed its Phase 1 clinical trial. The story of this vaccine is over 30 years in the making.