Orthopaedics
Experience Interdisciplinary Orthopaedic Research
Preclinical
Our researchers study a variety of orthopaedic diseases and conditions in a range of translational models from rodents to nonhuman primates, including specialized models of segmental defect, closed fracture, window defect, tendon repair, bone formation, and biocompatibility. Orthopaedic research at Wake Forest also makes use of capabilities in osteoclast and osteoblast cell cultures.
Key Areas of Research
- Nerve injury and repair
- Muscle composition changes due to age and injury
- Compartment syndrome monitoring
- Bone regeneration therapies
- Aging-related joint degeneration
- Rotator cuff tears
- Meniscus repair
- Tendon and ligament tissue engineering
- Brachial plexus birth palsy
- Stem cell therapies for orthopaedic applications
- Biomechanics
- Modeling and computational simulation
Clinical
Orthopaedic trauma research, in particular, is an area of expertise for Wake Forest Baptist clinicians. As a Level 1 Trauma Center, our orthopaedic surgeons and specialists see a high volume of patients with acute orthopaedic injuries in both adults and children from all over the region. This comprehensive population allows you to test your novel interventions for orthopaedic trauma from first admittance through rehabilitation.
Key Areas of Research
- Arterial reconstruction
- Nerve regeneration
- Therapeutic applications of botulinum neurotoxin
- Molecular markers and premature hip osteoarthritis
- Hand and upper extremity microsurgery
- Compartment syndrome
- Trauma
- Total join arthroplasty
- Stem cell applications
- Keratin biomaterials
- Pediatric orthopaedics
- Orthopaedic oncology
- Traumatic spinal cord injury
- Back pain and scoliosis
- Posture monitoring