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Christos Constantinidis, PhD

Christos Constantinidis, PhD, investigates the neurophysiology of cognitive function in nonhuman primate models. He is interested in collaborating with industry to discover techniques and treatments to improve working memory, visual perception and selective attention, as well as exploring the impact of behavioral and drug interventions on neuronal activity.


Christos Constantinidis, PhD

About Christos Constantinidis

In 1997, Christos Constantinidis, PhD, earned his doctorate in neuroscience from Johns Hopkins University, where he was first introduced to the study of neuronal activity in nonhuman primate models. He completed a postdoctoral research fellowship in neurobiology at the Yale School of Medicine before joining the neurobiology and anatomy department of Wake Forest School of Medicine in 2003.

Constantinidis’ research focuses on uncovering how neuronal activity in the brain impacts cognitive function. He is the principal investigator of a National Institutes of Health grant studying cognition maturation in a nonhuman primate model, examining how functional properties of neurons change in the prefrontal cortex from adolescence through adulthood. He also studies nonhuman primates to understand how computerized task training impacts visual cognition and the organization of cortical networks. His expertise in computational analysis and modeling advances these studies, enabling further investigation of patterns of neural activity and connectivity.

Other research efforts focus on improving cognitive function through deep brain stimulation and the use of embedded microelectrodes. Constantinidis studies how electric current impacts neural activity and silicone release in the brain with the goal of discovering new approaches for dementia and Alzheimer’s disease.

Constantinidis considers partnerships with industry essential for advancing the discovery of techniques and treatments to improve cognitive function, working memory and attention. He is specifically interested in collaborations exploring the impact of behavioral and drug interventions on neuronal activity.


Christos Constantinidis, PhD, professor of neurobiology and anatomy at Wake Forest School of Medicine, specializes in preclinical research of:

  • Neurosciences and Behavior
  • Attention
  • Memory and Higher Cognitive Function
  • Visual Processing
  • Computational Neuroscience
  • Deep Brain Stimulation