Featured Scientific Programs at Wake Forest

Wake Forest Innovations has the privilege of working with an outstanding group of scientists at Wake Forest Baptist Medical Center and Wake Forest University. We invite collaboration with our scientists. The Wake Forest Innovations team is available to assist you in finding scientific collaborations that can deliver great results.

Technology licensing by Wake Forest Innovations builds on the academic and clinical research expertise that have been the hallmarks of Wake Forest Baptist Medical Center for more than 70 years. This includes:

  • Scholarship in basic medical, materials and engineering science that attracts about $200 million in annual funding
  • Nationally recognized expertise in clinical research and practice
  • More than 1,095 Wake Forest School of Medicine faculty working in a diverse range of biomedical sciences

Wake Forest Baptist Medical Center has a successful track record in technology licensing and is recognized as one of the top five U.S. academic technology transfer offices for licensing income by the Association of University Technology Managers. It also is top ranked by Forbes.com for return on research investment.

Wake Forest University conducts a diverse range of research in areas ranging from the social to physical sciences. Many departments at the university are active in research with the departments of Biology, Chemistry, Physics and Computer Science. In addition to departmental research, research is conducted at a group of research centers in molecular signaling, energy, nanotechnology and translational science. The Center for Nanotechnology and Molecular Materials has established programs for working with industry, and participates in the newly formed Wake Forest Core Labs business initiative.

Our Featured Scientific Programs

Center for Comparative Medicine and Primate Center

The Center for Comparative Medicine at Wake Forest School of Medicine houses one of the nation’s oldest and most established academic primate centers and the only university-based nonhuman primate center devoted to preclinical research in the mid-Atlantic. For more than 50 years, investigators worldwide have used the Wake Forest Primate Center to conduct biomedical research, with the goal of advancing human health. The Primate Center has garnered an international reputation for its role in studies of cardiovascular disease, obesity and diabetes, breast and uterine cancer, depression and stress, and women’s health. More recently, new programs have been developed in aging, infectious diseases, vaccine development, and the late effects of radiation.

Learn more about the Wake Forest Primate Center.

Wake Forest Institute for Regenerative Medicine

The Wake Forest Institute for Regenerative Medicine (WFIRM) is an international leader in translating scientific discoveries into clinically successful therapies. The multidisciplinary environment at WFIRM enables investigators to effectively navigate the translational process. WFIRM has pioneered many research breakthroughs, as the first to:

  • Engineer functional experimental solid organs using a strategy of recycling donor organs, with potential applications to other organs, including the kidney and pancreas
  • Grow stem cells into functioning human bladders ex vivo, implant the organs into patients, and demonstrate normal complex function in human trials

Learn more about the Wake Forest Institute for Regenerative Medicine.

Population Science Program

Wake Forest Baptist Medical Center’s Division of Public Health Sciences is home to the Population Science Program, an important collaborative resource for national and international studies. The Population Science Program serves as a coordinating center for large, multicenter clinical trials and observational studies sponsored by the National Institutes of Health and industry. The program has one of the nation’s most concentrated collections of experts in:

  • Specialized statistical/epidemiological expertise in epidemiological genetics and statistical imaging analyses
  • Administrative expertise in contract management, expenditure monitoring and monitoring of data-use agreements
  • Local (large and small) computer and Web-based applications for clinical trials protocol, forms and manuals of procedures development
  • Regulatory input
  • Social science methodologies

The Population Science Program employs innovative scientific approaches to study design, implementation and analysis, including: large-scale Web-based technology for simple data collection and Web reports, mobile technology for various study needs, video-animation measurement tools for disability, and electronic cognition testing at sites and transmission of data to coordinating centers. Learn more about the Population Science Program.

Imaging Informatics Program

Wake Forest Baptist Medical Center’s Imaging Informatics Program develops quantitative phenotypes for the personalized medicine era. The program builds on more than two decades of experience with multicenter studies that have developed and standardized the techniques used to study heart disease, diabetes and neurocognitive function including: carotid intima-medial thickness, coronary artery calcium, visceral fat, pericardial fat, CT bone mineral density, liver steatosis, lung density, myocardial strain and neurofunctional MRI.

Expertise includes:

  • Designing imaging protocols that can be implemented in regional, national and international studies
  • Securely and efficiently moving large imaging datasets (plain film, CT, MRI, ultrasound, echocardiography and molecular imaging) from field sites to core labs for analysis
  • Archiving images, metadata and analysis results
  • Developing an imaging data and results warehouse using an ontological framework that facilitates information extraction and comparability between studies and modalities
  • Developing collaborative platforms for performing primary and secondary analysis of imaging phenotypes
  • Advancing analytics of imaging data, including pathway analysis, machine learning and neural networking techniques applied to imaging datasets

Learn more about the Imaging Programs.

The Sticht Center on Aging

Wake Forest Baptist Medical Center’s Aging Program builds on more than 25 years of national leadership in aging research and consists of three synergistic centers, aligned to provide broad expertise in aging.

The Sticht Center on Aging serves as the hub of research and teaching activities and is a key asset in the clinical treatment of elderly patients. The Center coordinates aging-related activities among 90 faculty from 21 different departments. Learn more about the Sticht Center on Aging.

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Where Innovation Lives


Where Innovation Lives